Provide your mice with a comfortable, dry, draught-free, clean home-cage in a quiet place where they can rest undisturbed. Make sure that where your mice live is safe, secure and free from hazards. Direct or bright lights should be avoided near the home-cage, however natural day light (not direct sunlight) should be present where they are housed. Make sure that their home-cage is kept away from high pitched sounds, ultrasound, and sudden bursts of noise.
Make sure their cage is clean with dry bedding and nesting material. It is important to maintain a balance between ensuring good health and avoiding excessive disturbance and stress when cleaning. Make sure that cages have good ventilation and air circulation without being draughty.
Provide your mice with objects that can be used as toilet areas or easily marked. This will allow them to communicate by using their odours. These objects should be easily cleaned, and should be cleaned as part of the regular cage cleaning routine.